The hunt for new drugs can be divided into two stages: discovery and development. Drug discovery includes generating a hypothesis of the target receptor for a particular disorder and screening the in vitro and/or in vivo biological activities of the new drug candidates. Drug development involves the assessment of efficacy and toxicity of the new drug candidates.
To aid in a discovery program, accurate data on pharmacokinetics and metabolism must be available as early as possible as it eventually contributes to the final success or failure of the compound.
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