{"id":3904,"date":"2024-10-01T17:11:34","date_gmt":"2024-10-01T15:11:34","guid":{"rendered":"https:\/\/amsbiopharma.com\/bioanalysis-and-biomakers\/"},"modified":"2026-09-23T15:04:36","modified_gmt":"2026-09-23T13:04:36","slug":"bioanalisis-y-biomarcadores","status":"publish","type":"page","link":"https:\/\/amsbiopharma.com\/es\/bioanalisis-y-biomarcadores\/","title":{"rendered":"Bioan\u00e1lisis y biomarcadores"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"3904\" class=\"elementor elementor-3904 elementor-488\" data-elementor-post-type=\"page\">\n\t\t\t\t<div class=\"elementor-element elementor-element-1a2acea8 e-flex e-con-boxed e-con e-parent\" data-id=\"1a2acea8\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-292da77a e-con-full e-flex e-con e-child\" data-id=\"292da77a\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-1c9a1f9d e-con-full e-flex e-con e-child\" data-id=\"1c9a1f9d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7e4bbd36 elementor-widget elementor-widget-heading\" data-id=\"7e4bbd36\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">An\u00e1lisis de Biomarcadores<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-61d112e5 e-con-full e-flex e-con e-child\" data-id=\"61d112e5\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;video&quot;,&quot;background_video_link&quot;:&quot;https:\\\/\\\/amsbiopharma.com\\\/wp-content\\\/uploads\\\/Clip10_Bioanalysis_Biomarkers.mp4&quot;,&quot;background_video_end&quot;:30}\">\n\t\t<div class=\"elementor-background-video-container elementor-hidden-mobile\">\n\t\t\t\t\t\t\t<video class=\"elementor-background-video-hosted\" role=\"presentation\" autoplay muted playsinline loop><\/video>\n\t\t\t\t\t<\/div><div class=\"elementor-element elementor-element-e7e54a3 e-con-full e-flex e-con e-child\" data-id=\"e7e54a3\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;video&quot;,&quot;background_video_link&quot;:&quot;https:\\\/\\\/amsbiopharma.com\\\/wp-content\\\/uploads\\\/Clip10_Bioanalysis_Biomarkers2.mp4&quot;,&quot;background_play_on_mobile&quot;:&quot;yes&quot;,&quot;background_play_once&quot;:&quot;yes&quot;,&quot;background_video_end&quot;:13,&quot;background_video_start&quot;:0}\">\n\t\t<div class=\"elementor-background-video-container\">\n\t\t\t\t\t\t\t<video class=\"elementor-background-video-hosted\" role=\"presentation\" autoplay muted playsinline><\/video>\n\t\t\t\t\t<\/div>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8e2d49b e-flex e-con-boxed e-con e-parent\" data-id=\"8e2d49b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-2ce3633 e-con-full e-flex e-con e-child\" data-id=\"2ce3633\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9b7c836 elementor-widget elementor-widget-heading\" data-id=\"9b7c836\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Servicios integrales validados de an\u00e1lisis de biomarcadores en todas las \u00e1reas terap\u00e9uticas y fases de desarrollo.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d6afdf6 elementor-widget elementor-widget-text-editor\" data-id=\"d6afdf6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Los <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\"> se han convertido en herramientas indispensables en el desarrollo moderno de f\u00e1rmacos, proporcionando medidas objetivas y cuantitativas de procesos biol\u00f3gicos, respuestas farmacol\u00f3gicas y estados de enfermedad que informan cada decisi\u00f3n cl\u00ednica y regulatoria. La calidad anal\u00edtica de los datos de <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\"> determina su validez cient\u00edfica y regulatoria.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">AMSbiopharma ofrece una amplia cartera de servicios de an\u00e1lisis de <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\">, cubriendo <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\"> de enfermedad, de seguridad, farmacodin\u00e1micos y de respuesta en m\u00faltiples \u00e1reas terap\u00e9uticas. Nuestro equipo combina profunda experiencia bioanal\u00edtica con un conocimiento exhaustivo de la estrategia de <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Todos los m\u00e9todos anal\u00edticos se desarrollan y validan con est\u00e1ndares adaptados al prop\u00f3sito, desde m\u00e9todos exploratorios hasta m\u00e9todos completamente validados que respaldan presentaciones regulatorias de <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a2cd724 e-con-full e-flex e-con e-child\" data-id=\"a2cd724\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;sticky&quot;:&quot;top&quot;,&quot;sticky_offset&quot;:100,&quot;sticky_anchor_link_offset&quot;:100,&quot;sticky_parent&quot;:&quot;yes&quot;,&quot;sticky_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;,&quot;mobile&quot;],&quot;sticky_effects_offset&quot;:0}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-3604d60 elementor-widget elementor-widget-image\" data-id=\"3604d60\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"900\" height=\"771\" src=\"https:\/\/amsbiopharma.com\/wp-content\/uploads\/img.png\" class=\"attachment-large size-large wp-image-3616\" alt=\"\" srcset=\"https:\/\/amsbiopharma.com\/wp-content\/uploads\/img.png 900w, https:\/\/amsbiopharma.com\/wp-content\/uploads\/img-300x257.png 300w, https:\/\/amsbiopharma.com\/wp-content\/uploads\/img-768x658.png 768w\" sizes=\"(max-width: 900px) 100vw, 900px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-87d0c11 e-con-full e-flex e-con e-parent\" data-id=\"87d0c11\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t<div class=\"elementor-element elementor-element-223d97b e-con-full e-flex e-con e-child\" data-id=\"223d97b\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-417f340 elementor-widget elementor-widget-heading\" data-id=\"417f340\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Nuestro cat\u00e1logo de servicios incluye<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9da3625 e-con-full e-grid e-con e-child\" data-id=\"9da3625\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-32171b7 elementor-widget elementor-widget-image\" data-id=\"32171b7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"2156\" height=\"1641\" src=\"https:\/\/amsbiopharma.com\/wp-content\/uploads\/AM_2026_04_01_BLOG-1.webp\" class=\"attachment-full size-full wp-image-6147\" alt=\"Aplicaciones de Metabol\u00f3mica\" srcset=\"https:\/\/amsbiopharma.com\/wp-content\/uploads\/AM_2026_04_01_BLOG-1.webp 2156w, https:\/\/amsbiopharma.com\/wp-content\/uploads\/AM_2026_04_01_BLOG-1-300x228.webp 300w, https:\/\/amsbiopharma.com\/wp-content\/uploads\/AM_2026_04_01_BLOG-1-1024x779.webp 1024w, https:\/\/amsbiopharma.com\/wp-content\/uploads\/AM_2026_04_01_BLOG-1-768x585.webp 768w, https:\/\/amsbiopharma.com\/wp-content\/uploads\/AM_2026_04_01_BLOG-1-1536x1169.webp 1536w, https:\/\/amsbiopharma.com\/wp-content\/uploads\/AM_2026_04_01_BLOG-1-2048x1559.webp 2048w\" sizes=\"(max-width: 2156px) 100vw, 2156px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d6f3f50 elementor-widget elementor-widget-n-accordion\" data-id=\"d6f3f50\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;default_state&quot;:&quot;expanded&quot;,&quot;max_items_expended&quot;:&quot;one&quot;,&quot;n_accordion_animation_duration&quot;:{&quot;unit&quot;:&quot;ms&quot;,&quot;size&quot;:400,&quot;sizes&quot;:[]}}\" data-widget_type=\"nested-accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"e-n-accordion\" aria-label=\"Accordion. Open links with Enter or Space, close with Escape, and navigate with Arrow Keys\">\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2250\" class=\"e-n-accordion-item\" open>\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"1\" tabindex=\"0\" aria-expanded=\"true\" aria-controls=\"e-n-accordion-item-2250\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><h3 class=\"e-n-accordion-item-title-text\"> An\u00e1lisis de Biomarcadores Inflamatorios \/ NON GLP <\/h3><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-alt-circle-down\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M504 256c0 137-111 248-248 248S8 393 8 256 119 8 256 8s248 111 248 248zM212 140v116h-70.9c-10.7 0-16.1 13-8.5 20.5l114.9 114.3c4.7 4.7 12.2 4.7 16.9 0l114.9-114.3c7.6-7.6 2.2-20.5-8.5-20.5H300V140c0-6.6-5.4-12-12-12h-64c-6.6 0-12 5.4-12 12z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-alt-circle-right\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8c137 0 248 111 248 248S393 504 256 504 8 393 8 256 119 8 256 8zM140 300h116v70.9c0 10.7 13 16.1 20.5 8.5l114.3-114.9c4.7-4.7 4.7-12.2 0-16.9l-114.3-115c-7.6-7.6-20.5-2.2-20.5 8.5V212H140c-6.6 0-12 5.4-12 12v64c0 6.6 5.4 12 12 12z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2250\" class=\"elementor-element elementor-element-d25419b e-con-full e-flex e-con e-child\" data-id=\"d25419b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2250\" class=\"elementor-element elementor-element-d37403f e-flex e-con-boxed e-con e-child\" data-id=\"d37403f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-cde2690 elementor-widget elementor-widget-text-editor\" data-id=\"cde2690\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Los <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\"> inflamatorios se encuentran entre los endpoints m\u00e1s evaluados en el desarrollo farmac\u00e9utico, proporcionando datos mecan\u00edsticos, farmacodin\u00e1micos y de seguridad cr\u00edticos en inmunolog\u00eda, oncolog\u00eda, enfermedades autoinmunes, metab\u00f3licas y del <\/span><b>CNS<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">AMSbiopharma proporciona tanto cuantificaci\u00f3n dirigida de marcadores inflamatorios espec\u00edficos como enfoques de perfilado de panel amplio. Los ensayos dirigidos ofrecen la precisi\u00f3n y el estado de validaci\u00f3n requeridos para datos farmacodin\u00e1micos de calidad regulatoria, mientras que los enfoques de panel amplio permiten el perfilado inflamatorio integral para programas de descubrimiento de <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><b>Capacidades anal\u00edticas clave:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cuantificaci\u00f3n dirigida de citocinas individuales, quimiocinas y prote\u00ednas de fase aguda<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Perfilado inflamatorio de panel amplio para descubrimiento de <\/span><b>biomarcadores<\/b><\/li>\n<p> \t<\/p>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Desarrollo de m\u00e9todos validados en plasma, suero y matrices tisulares<\/span><\/li>\n<p> \t<\/p>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aplicable en inmunolog\u00eda, oncolog\u00eda, enfermedades autoinmunes y metab\u00f3licas<\/span><\/li>\n<p><\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2251\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"2\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2251\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><h3 class=\"e-n-accordion-item-title-text\"> An\u00e1lisis de Biomarcadores Vasculares y de Angiog\u00e9nesis \/ NON GLP <\/h3><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-alt-circle-down\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M504 256c0 137-111 248-248 248S8 393 8 256 119 8 256 8s248 111 248 248zM212 140v116h-70.9c-10.7 0-16.1 13-8.5 20.5l114.9 114.3c4.7 4.7 12.2 4.7 16.9 0l114.9-114.3c7.6-7.6 2.2-20.5-8.5-20.5H300V140c0-6.6-5.4-12-12-12h-64c-6.6 0-12 5.4-12 12z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-alt-circle-right\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8c137 0 248 111 248 248S393 504 256 504 8 393 8 256 119 8 256 8zM140 300h116v70.9c0 10.7 13 16.1 20.5 8.5l114.3-114.9c4.7-4.7 4.7-12.2 0-16.9l-114.3-115c-7.6-7.6-20.5-2.2-20.5 8.5V212H140c-6.6 0-12 5.4-12 12v64c0 6.6 5.4 12 12 12z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2251\" class=\"elementor-element elementor-element-ce5a16e e-con-full e-flex e-con e-child\" data-id=\"ce5a16e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2251\" class=\"elementor-element elementor-element-b25c7dc e-flex e-con-boxed e-con e-child\" data-id=\"b25c7dc\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-56d5c9f elementor-widget elementor-widget-text-editor\" data-id=\"56d5c9f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Los <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\"> vasculares y angiog\u00e9nicos desempe\u00f1an un papel central en oncolog\u00eda, enfermedades cardiovasculares y oftalmolog\u00eda. Mediadores clave como el <\/span><b>VEGF<\/b><span style=\"font-weight: 400;\">, el <\/span><b>PDGF<\/b><span style=\"font-weight: 400;\"> y las angiopoyetinas son endpoints farmacodin\u00e1micos relevantes en programas de terapia anti-angiog\u00e9nica.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">AMSbiopharma ofrece servicios anal\u00edticos validados para la cuantificaci\u00f3n de prote\u00ednas y mediadores vasculares en matrices biol\u00f3gicas, apoyando estudios mecan\u00edsticos y evaluaci\u00f3n del compromiso de diana.<\/span><\/p>\n<p><b>Capacidades anal\u00edticas clave:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cuantificaci\u00f3n de <\/span><b>VEGF<\/b><span style=\"font-weight: 400;\">, <\/span><b>PDGF<\/b><span style=\"font-weight: 400;\">, angiopoyetinas<\/span> <span style=\"font-weight: 400;\"> y <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\"> vasculares relacionados<\/span><\/li>\n<p> \t<\/p>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Desarrollo de m\u00e9todos en plasma, suero, tejido y otras matrices biol\u00f3gicas<\/span><\/li>\n<p> \t<\/p>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Soporte para monitorizaci\u00f3n farmacodin\u00e1mica en programas anti-angiog\u00e9nicos<\/span><\/li>\n<p> \t<\/p>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aplicable en oncolog\u00eda, enfermedades cardiovasculares y oftalmolog\u00eda<\/span><\/li>\n<p><\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2252\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"3\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2252\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><h3 class=\"e-n-accordion-item-title-text\"> An\u00e1lisis de Biomarcadores de Enfermedad Sist\u00e9mica \/ NON GLP <\/h3><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-alt-circle-down\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M504 256c0 137-111 248-248 248S8 393 8 256 119 8 256 8s248 111 248 248zM212 140v116h-70.9c-10.7 0-16.1 13-8.5 20.5l114.9 114.3c4.7 4.7 12.2 4.7 16.9 0l114.9-114.3c7.6-7.6 2.2-20.5-8.5-20.5H300V140c0-6.6-5.4-12-12-12h-64c-6.6 0-12 5.4-12 12z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-alt-circle-right\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8c137 0 248 111 248 248S393 504 256 504 8 393 8 256 119 8 256 8zM140 300h116v70.9c0 10.7 13 16.1 20.5 8.5l114.3-114.9c4.7-4.7 4.7-12.2 0-16.9l-114.3-115c-7.6-7.6-20.5-2.2-20.5 8.5V212H140c-6.6 0-12 5.4-12 12v64c0 6.6 5.4 12 12 12z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2252\" class=\"elementor-element elementor-element-58587a7 e-con-full e-flex e-con e-child\" data-id=\"58587a7\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2252\" class=\"elementor-element elementor-element-3111355 e-flex e-con-boxed e-con e-child\" data-id=\"3111355\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-18360ab elementor-widget elementor-widget-text-editor\" data-id=\"18360ab\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Los <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\"> de enfermedad sist\u00e9mica proporcionan informaci\u00f3n diagn\u00f3stica, pron\u00f3stica y farmacodin\u00e1mica esencial en un amplio rango de \u00e1reas terap\u00e9uticas.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">AMSbiopharma ofrece el desarrollo de servicios validados para la cuantificaci\u00f3n de prote\u00ednas, enzimas, metabolitos y otras entidades moleculares asociadas a enfermedades en muestras biol\u00f3gicas, con calidad de datos alineada con los requisitos de presentaciones regulatorias de <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\"> y v\u00edas de desarrollo de diagn\u00f3sticos complementarios.<\/span><\/p>\n<p><b>Capacidades anal\u00edticas clave:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cuantificaci\u00f3n de prote\u00ednas, enzimas y metabolitos asociados a enfermedades<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aplicable en m\u00faltiples \u00e1reas terap\u00e9uticas y estados de enfermedad<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Desarrollo de m\u00e9todos validados para monitorizaci\u00f3n farmacodin\u00e1mica en ensayos cl\u00ednicos<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Paquetes de datos alineados con las directrices de <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\"> de <\/span><b>FDA<\/b><span style=\"font-weight: 400;\"> y <\/span><b>EMA<\/b><\/li>\n<p><\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2253\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"4\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2253\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><h3 class=\"e-n-accordion-item-title-text\"> Biomarcadores de Oncolog\u00eda \/ NON GLP <\/h3><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-alt-circle-down\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M504 256c0 137-111 248-248 248S8 393 8 256 119 8 256 8s248 111 248 248zM212 140v116h-70.9c-10.7 0-16.1 13-8.5 20.5l114.9 114.3c4.7 4.7 12.2 4.7 16.9 0l114.9-114.3c7.6-7.6 2.2-20.5-8.5-20.5H300V140c0-6.6-5.4-12-12-12h-64c-6.6 0-12 5.4-12 12z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-alt-circle-right\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8c137 0 248 111 248 248S393 504 256 504 8 393 8 256 119 8 256 8zM140 300h116v70.9c0 10.7 13 16.1 20.5 8.5l114.3-114.9c4.7-4.7 4.7-12.2 0-16.9l-114.3-115c-7.6-7.6-20.5-2.2-20.5 8.5V212H140c-6.6 0-12 5.4-12 12v64c0 6.6 5.4 12 12 12z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2253\" class=\"elementor-element elementor-element-e0f3f88 e-con-full e-flex e-con e-child\" data-id=\"e0f3f88\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2253\" class=\"elementor-element elementor-element-25b3c26 e-flex e-con-boxed e-con e-child\" data-id=\"25b3c26\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-877d61b elementor-widget elementor-widget-text-editor\" data-id=\"877d61b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Los <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\"> oncol\u00f3gicos son elementos centrales del dise\u00f1o de los ensayos cl\u00ednicos modernos, permitiendo la selecci\u00f3n de pacientes basada en el estado del <\/span><b>biomarcador<\/b><span style=\"font-weight: 400;\"> predictivo, la monitorizaci\u00f3n farmacodin\u00e1mica del compromiso de diana y el desarrollo de diagn\u00f3sticos complementarios.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">AMSbiopharma ofrece el desarrollo de servicios <\/span><b>bioanal\u00edticos<\/b><span style=\"font-weight: 400;\"> para la cuantificaci\u00f3n de prote\u00ednas asociadas a tumores, <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\"> circulantes<\/span><span style=\"font-weight: 400;\">, endpoints farmacodin\u00e1micos y marcadores de respuesta en plasma, suero, tejido tumoral y <\/span><span style=\"font-weight: 400;\">muestras de <\/span><b>biopsia l\u00edquida<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><b>Capacidades anal\u00edticas clave:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cuantificaci\u00f3n de <\/span><span style=\"font-weight: 400;\">marcadores tumorales circulantes<\/span><span style=\"font-weight: 400;\"> y endpoints farmacodin\u00e1micos<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">M\u00e9todos validados en plasma, suero, tejido y <\/span><b>biopsia l\u00edquida<\/b><\/li>\n<p> \t<\/p>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">An\u00e1lisis de <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\"> de estratificaci\u00f3n de pacientes para ensayos cl\u00ednicos de oncolog\u00eda<\/span><\/li>\n<p> \t<\/p>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aplicable en inmuno-oncolog\u00eda, terapia dirigida y programas de <\/span><b>ADC<\/b><\/li>\n<p><\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2254\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"5\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2254\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><h3 class=\"e-n-accordion-item-title-text\"> An\u00e1lisis de Biomarcadores de Aminas Bi\u00f3genas \/ NON GLP <\/h3><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-alt-circle-down\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M504 256c0 137-111 248-248 248S8 393 8 256 119 8 256 8s248 111 248 248zM212 140v116h-70.9c-10.7 0-16.1 13-8.5 20.5l114.9 114.3c4.7 4.7 12.2 4.7 16.9 0l114.9-114.3c7.6-7.6 2.2-20.5-8.5-20.5H300V140c0-6.6-5.4-12-12-12h-64c-6.6 0-12 5.4-12 12z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-alt-circle-right\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8c137 0 248 111 248 248S393 504 256 504 8 393 8 256 119 8 256 8zM140 300h116v70.9c0 10.7 13 16.1 20.5 8.5l114.3-114.9c4.7-4.7 4.7-12.2 0-16.9l-114.3-115c-7.6-7.6-20.5-2.2-20.5 8.5V212H140c-6.6 0-12 5.4-12 12v64c0 6.6 5.4 12 12 12z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2254\" class=\"elementor-element elementor-element-3240bd8 e-con-full e-flex e-con e-child\" data-id=\"3240bd8\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2254\" class=\"elementor-element elementor-element-e6e94de e-flex e-con-boxed e-con e-child\" data-id=\"e6e94de\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ac6ba7e elementor-widget elementor-widget-text-editor\" data-id=\"ac6ba7e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Las <\/span><b>aminas bi\u00f3genas<\/b><span style=\"font-weight: 400;\"> \u2014serotonina, dopamina, norepinefrina, epinefrina, histamina y sus metabolitos\u2014 son <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\"> farmacodin\u00e1micos y de seguridad relevantes en programas del <\/span><b>CNS<\/b><span style=\"font-weight: 400;\">, cardiovasculares y oncol\u00f3gicos.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">AMSbiopharma ofrece servicios anal\u00edticos validados para la cuantificaci\u00f3n de <\/span><b>aminas bi\u00f3genas<\/b><span style=\"font-weight: 400;\"> en plasma, orina, <\/span><b>LCR<\/b><span style=\"font-weight: 400;\"> y tejido, aplicando m\u00e9todos sensibles basados en <\/span><b>LC-MS\/MS<\/b><span style=\"font-weight: 400;\"> con la selectividad requerida para programas de <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\"> farmacodin\u00e1micos y de seguridad.<\/span><\/p>\n<p><b>Capacidades anal\u00edticas clave:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cuantificaci\u00f3n de serotonina, dopamina, norepinefrina, epinefrina y metabolitos<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Desarrollo de m\u00e9todos <\/span><b>LC-MS\/MS<\/b><span style=\"font-weight: 400;\"> validados en plasma, orina, <\/span><b>LCR<\/b><span style=\"font-weight: 400;\"> y tejido<\/span><\/li>\n<p> \t<\/p>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aplicable en programas del <\/span><b>CNS<\/b><span style=\"font-weight: 400;\">, cardiovasculares y oncol\u00f3gicos<\/span><\/li>\n<p> \t<\/p>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Desarrollo de m\u00e9todos que resuelven especies de <\/span><b>aminas bi\u00f3genas<\/b><span style=\"font-weight: 400;\"> estructuralmente similares<\/span><\/li>\n<p><\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2255\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"6\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2255\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><h3 class=\"e-n-accordion-item-title-text\"> An\u00e1lisis de Biomarcadores de Ceramidas y Esfingosinas \/ NON GLP <\/h3><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-alt-circle-down\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M504 256c0 137-111 248-248 248S8 393 8 256 119 8 256 8s248 111 248 248zM212 140v116h-70.9c-10.7 0-16.1 13-8.5 20.5l114.9 114.3c4.7 4.7 12.2 4.7 16.9 0l114.9-114.3c7.6-7.6 2.2-20.5-8.5-20.5H300V140c0-6.6-5.4-12-12-12h-64c-6.6 0-12 5.4-12 12z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-alt-circle-right\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8c137 0 248 111 248 248S393 504 256 504 8 393 8 256 119 8 256 8zM140 300h116v70.9c0 10.7 13 16.1 20.5 8.5l114.3-114.9c4.7-4.7 4.7-12.2 0-16.9l-114.3-115c-7.6-7.6-20.5-2.2-20.5 8.5V212H140c-6.6 0-12 5.4-12 12v64c0 6.6 5.4 12 12 12z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2255\" class=\"elementor-element elementor-element-d9eda51 e-con-full e-flex e-con e-child\" data-id=\"d9eda51\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2255\" class=\"elementor-element elementor-element-6113535 e-flex e-con-boxed e-con e-child\" data-id=\"6113535\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0234a2f elementor-widget elementor-widget-text-editor\" data-id=\"0234a2f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Las <\/span><b>ceramidas<\/b><span style=\"font-weight: 400;\"> y <\/span><b>esfingosinas<\/b><span style=\"font-weight: 400;\"> son especies lip\u00eddicas bioactivas con relevancia emergente como <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\"> en la estratificaci\u00f3n del riesgo cardiovascular, las enfermedades metab\u00f3licas y la oncolog\u00eda.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">AMSbiopharma proporciona servicios validados basados en <\/span><b>LC-MS\/MS<\/b><span style=\"font-weight: 400;\"> para la cuantificaci\u00f3n dirigida de especies individuales de <\/span><b>ceramidas<\/b><span style=\"font-weight: 400;\"> y <\/span><b>esfingosinas<\/b><span style=\"font-weight: 400;\"> en plasma, suero y otras matrices biol\u00f3gicas, con la especificidad requerida para la calificaci\u00f3n de <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><b>Capacidades anal\u00edticas clave:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cuantificaci\u00f3n dirigida de especies individuales de <\/span><b>ceramidas<\/b><span style=\"font-weight: 400;\"> y <\/span><b>esfingosinas<\/b><\/li>\n<p> \t<\/p>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Desarrollo de m\u00e9todos <\/span><b>LC-MS\/MS<\/b><span style=\"font-weight: 400;\"> validados con alta sensibilidad y selectividad<\/span><\/li>\n<p> \t<\/p>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Calidad de datos alineada con las directrices regulatorias<\/span><\/li>\n<p><\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2256\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"7\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2256\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><h3 class=\"e-n-accordion-item-title-text\"> An\u00e1lisis de Biomarcadores de Cortisol \/ NON GLP <\/h3><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-alt-circle-down\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M504 256c0 137-111 248-248 248S8 393 8 256 119 8 256 8s248 111 248 248zM212 140v116h-70.9c-10.7 0-16.1 13-8.5 20.5l114.9 114.3c4.7 4.7 12.2 4.7 16.9 0l114.9-114.3c7.6-7.6 2.2-20.5-8.5-20.5H300V140c0-6.6-5.4-12-12-12h-64c-6.6 0-12 5.4-12 12z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-alt-circle-right\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8c137 0 248 111 248 248S393 504 256 504 8 393 8 256 119 8 256 8zM140 300h116v70.9c0 10.7 13 16.1 20.5 8.5l114.3-114.9c4.7-4.7 4.7-12.2 0-16.9l-114.3-115c-7.6-7.6-20.5-2.2-20.5 8.5V212H140c-6.6 0-12 5.4-12 12v64c0 6.6 5.4 12 12 12z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2256\" class=\"elementor-element elementor-element-afa84f9 e-con-full e-flex e-con e-child\" data-id=\"afa84f9\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2256\" class=\"elementor-element elementor-element-376c97b e-flex e-con-boxed e-con e-child\" data-id=\"376c97b\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-db3b34a elementor-widget elementor-widget-text-editor\" data-id=\"db3b34a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">El <\/span><b>cortisol<\/b><span style=\"font-weight: 400;\"> es un <\/span><b>biomarcador<\/b><span style=\"font-weight: 400;\"> cr\u00edtico en endocrinolog\u00eda, fisiolog\u00eda del estr\u00e9s y funci\u00f3n del eje HHA, con relevancia en el desarrollo terap\u00e9utico del <\/span><b>CNS<\/b><span style=\"font-weight: 400;\">, enfermedades metab\u00f3licas, oncolog\u00eda y endocrinolog\u00eda.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">AMSbiopharma proporciona el desarrollo de servicios anal\u00edticos validados para la cuantificaci\u00f3n de <\/span><b>cortisol<\/b><span style=\"font-weight: 400;\"> en plasma, suero, orina y saliva, aplicando m\u00e9todos cromatogr\u00e1ficos validados con la sensibilidad y especificidad adecuadas para programas precl\u00ednicos y cl\u00ednicos.<\/span><\/p>\n<p><b>Capacidades anal\u00edticas clave:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cuantificaci\u00f3n de <\/span><b>cortisol<\/b><span style=\"font-weight: 400;\"> en plasma, suero, orina y saliva<\/span><\/li>\n<p> \t<\/p>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Desarrollo de m\u00e9todos validados con sensibilidad adecuada para la monitorizaci\u00f3n de la variaci\u00f3n circadiana<\/span><\/li>\n<p> \t<\/p>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aplicable en programas del <\/span><b>CNS<\/b><span style=\"font-weight: 400;\">, endocrinolog\u00eda y enfermedades metab\u00f3licas<\/span><\/li>\n<p><\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t\t<details id=\"e-n-accordion-item-2257\" class=\"e-n-accordion-item\" >\n\t\t\t\t<summary class=\"e-n-accordion-item-title\" data-accordion-index=\"8\" tabindex=\"-1\" aria-expanded=\"false\" aria-controls=\"e-n-accordion-item-2257\" >\n\t\t\t\t\t<span class='e-n-accordion-item-title-header'><h3 class=\"e-n-accordion-item-title-text\"> An\u00e1lisis de Biomarcadores de Esfingol\u00edpidos \/ NON GLP <\/h3><\/span>\n\t\t\t\t\t\t\t<span class='e-n-accordion-item-title-icon'>\n\t\t\t<span class='e-opened' ><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-alt-circle-down\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M504 256c0 137-111 248-248 248S8 393 8 256 119 8 256 8s248 111 248 248zM212 140v116h-70.9c-10.7 0-16.1 13-8.5 20.5l114.9 114.3c4.7 4.7 12.2 4.7 16.9 0l114.9-114.3c7.6-7.6 2.2-20.5-8.5-20.5H300V140c0-6.6-5.4-12-12-12h-64c-6.6 0-12 5.4-12 12z\"><\/path><\/svg><\/span>\n\t\t\t<span class='e-closed'><svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-arrow-alt-circle-right\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8c137 0 248 111 248 248S393 504 256 504 8 393 8 256 119 8 256 8zM140 300h116v70.9c0 10.7 13 16.1 20.5 8.5l114.3-114.9c4.7-4.7 4.7-12.2 0-16.9l-114.3-115c-7.6-7.6-20.5-2.2-20.5 8.5V212H140c-6.6 0-12 5.4-12 12v64c0 6.6 5.4 12 12 12z\"><\/path><\/svg><\/span>\n\t\t<\/span>\n\n\t\t\t\t\t\t<\/summary>\n\t\t\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2257\" class=\"elementor-element elementor-element-99dd8e8 e-con-full e-flex e-con e-child\" data-id=\"99dd8e8\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div role=\"region\" aria-labelledby=\"e-n-accordion-item-2257\" class=\"elementor-element elementor-element-6e26c3f e-flex e-con-boxed e-con e-child\" data-id=\"6e26c3f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-129d42c elementor-widget elementor-widget-text-editor\" data-id=\"129d42c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">Los <\/span><b>esfingol\u00edpidos<\/b><span style=\"font-weight: 400;\"> son mol\u00e9culas lip\u00eddicas bioactivas con roles establecidos en la estructura de membranas, la se\u00f1alizaci\u00f3n celular y las respuestas inflamatorias. El esfingolipidoma ha emergido como fuente importante de <\/span><b>biomarcadores<\/b><span style=\"font-weight: 400;\"> en enfermedades metab\u00f3licas, neurol\u00f3gicas e inflamatorias y en oncolog\u00eda.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">AMSbiopharma ofrece servicios basados en <\/span><b>LC-MS\/MS<\/b><span style=\"font-weight: 400;\"> para la cuantificaci\u00f3n dirigida y el perfilado de especies de <\/span><b>esfingol\u00edpidos<\/b><span style=\"font-weight: 400;\"> en matrices biol\u00f3gicas, proporcionando la selectividad anal\u00edtica requerida para distinguir y cuantificar especies moleculares individuales.<\/span><\/p>\n<p><b>Capacidades anal\u00edticas clave:<\/b><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Cuantificaci\u00f3n dirigida y perfilado de <\/span><b>esfingol\u00edpidos<\/b><span style=\"font-weight: 400;\"> por <\/span><b>LC-MS\/MS<\/b><\/li>\n<p> \t<\/p>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Aplicable en enfermedades metab\u00f3licas, neurol\u00f3gicas e inflamatorias<\/span><\/li>\n<p> \t<\/p>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">M\u00e9todos validados para estudios cl\u00ednicos de <\/span><b>biomarcadores<\/b><\/li>\n<p> \t<\/p>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Calidad y reproducibilidad alineadas con las expectativas regulatorias<\/span><\/li>\n<p><\/ul>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/details>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-569a767 e-con-full e-flex e-con e-parent\" data-id=\"569a767\" data-element_type=\"container\" data-e-type=\"container\" id=\"discover-menu-container\">\n\t\t<div class=\"elementor-element elementor-element-60d507a e-con-full title-container e-flex e-con e-child\" data-id=\"60d507a\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ad48d71 elementor-widget elementor-widget-heading\" data-id=\"ad48d71\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Descubre<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-461c7f6 elementor-widget elementor-widget-html\" data-id=\"461c7f6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-plus-circle\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M256 8C119 8 8 119 8 256s111 248 248 248 248-111 248-248S393 8 256 8zm144 276c0 6.6-5.4 12-12 12h-92v92c0 6.6-5.4 12-12 12h-56c-6.6 0-12-5.4-12-12v-92h-92c-6.6 0-12-5.4-12-12v-56c0-6.6 5.4-12 12-12h92v-92c0-6.6 5.4-12 12-12h56c6.6 0 12 5.4 12 12v92h92c6.6 0 12 5.4 12 12v56z\"><\/path><\/svg>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-277ed7c elementor-nav-menu--dropdown-none discover-menu elementor-widget elementor-widget-nav-menu\" data-id=\"277ed7c\" data-element_type=\"widget\" data-e-type=\"widget\" data-settings=\"{&quot;layout&quot;:&quot;vertical&quot;,&quot;submenu_icon&quot;:{&quot;value&quot;:&quot;&lt;svg aria-hidden=\\&quot;true\\&quot; 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Los biomarcadores se han convertido en herramientas indispensables en el desarrollo moderno de f\u00e1rmacos, proporcionando medidas objetivas y cuantitativas de procesos&hellip;\n<\/div>\n<div class=\"link-more\"><a href=\"https:\/\/amsbiopharma.com\/es\/bioanalisis-y-biomarcadores\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &ldquo;Bioan\u00e1lisis y biomarcadores&rdquo;<\/span>&hellip;<\/a><\/div>\n","protected":false},"author":1,"featured_media":4763,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-3904","page","type-page","status-publish","has-post-thumbnail","hentry","entry"],"_links":{"self":[{"href":"https:\/\/amsbiopharma.com\/es\/wp-json\/wp\/v2\/pages\/3904","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/amsbiopharma.com\/es\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/amsbiopharma.com\/es\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/amsbiopharma.com\/es\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/amsbiopharma.com\/es\/wp-json\/wp\/v2\/comments?post=3904"}],"version-history":[{"count":41,"href":"https:\/\/amsbiopharma.com\/es\/wp-json\/wp\/v2\/pages\/3904\/revisions"}],"predecessor-version":[{"id":6911,"href":"https:\/\/amsbiopharma.com\/es\/wp-json\/wp\/v2\/pages\/3904\/revisions\/6911"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/amsbiopharma.com\/es\/wp-json\/wp\/v2\/media\/4763"}],"wp:attachment":[{"href":"https:\/\/amsbiopharma.com\/es\/wp-json\/wp\/v2\/media?parent=3904"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}